Recurrent tumors

• Recurrent malignant tumors seem to be more aggressive than the original tumor.
• The lungs are the most common metastatic site, followed by the skeleton, heart, and liver.
• Symptoms from metastatic involvement can arise from as early as a few months to as late as 12 years after the initial therapy.
• Most patients with metastases die within 3 years of the initial treatment.
• No cures for systemic metastases exist.
• Roughly 30% of patients with malignant phyllodes tumors die from the disease.